- Kenema is a city in the Eastern Province of Sierra Leone, located in West Africa. It is the third largest city in Sierra Leone and serves as a major economic and administrative center for the region. Kenema is known for its vibrant markets, as well as its role in the diamond and agricultural industries. The city has a rich cultural heritage, with various ethnic groups residing in the area, including the Kono, Mende, and Loko people. Kenema is also home to the Kenema Government Hospital, which played a crucial role in combating the Ebola virus disease outbreak in Sierra Leone in 2014.